---
type: "post"
id: "fighting-back-an-experimental-treatment-has-helped-people-853c71"
slug: "fighting-back-an-experimental-treatment-has-helped-people-853c71"
title: "Fighting Back: An experimental treatment has helped people with stiff person syndrome regain movement and dramatically reduce falls."
description: "Science News reports that an experimental CAR T-cell therapy has restored substantial mobility for people with stiff person syndrome, a rare autoimmune disease that causes rigidity, spasms and falls."
retrieval_nugget: "Science News reports that an experimental CAR T-cell therapy has restored substantial mobility for people with stiff person syndrome, a rare autoimmune disease that causes rigidity, spasms and falls."
published_at: "2026-10-25"
updated_at: "2026-10-25"
record_date: "2026-10-25"
date_kind: "published_at"
topics: ["ai"]
entities: ["CAR T-cell therapy","University of Colorado Anschutz","U.S. Food and Drug Administration","University of Pennsylvania","Carl June","Amanda Piquet"]
related_patterns: []
novelty_label: "new_fact"
what_changed: "Reports an experimental CAR-T treatment helping a stiff person syndrome patient regain mobility and reduce falls; none of the supplied priors covers this treatment or condition."
prior_refs: []
source_url: "https://www.sciencenews.org/article/car-t-cell-therapy-autoimmune-diseases"
source_urls: ["https://www.sciencenews.org/article/car-t-cell-therapy-autoimmune-diseases"]
schema_version: "newruntime-agent-readable-v0.2"
stable_id: "post:fighting-back-an-experimental-treatment-has-helped-people-853c71"
status: "published"
visuals: []
editor: {"role":"editor","name":"Andrey Reshetnikov","profile":"https://newruntime.com/owner-profile.md","profile_json":"https://newruntime.com/owner-profile.json","same_as":["https://www.linkedin.com/in/reshetnikov1/","https://t.me/lapetuse"]}
routes: {"html":"https://newruntime.com/posts/fighting-back-an-experimental-treatment-has-helped-people-853c71/","markdown":"https://newruntime.com/posts/fighting-back-an-experimental-treatment-has-helped-people-853c71.md","json":"https://newruntime.com/posts/fighting-back-an-experimental-treatment-has-helped-people-853c71.json"}
---

# Fighting Back: An experimental treatment has helped people with stiff person syndrome regain movement and dramatically reduce falls.

## Retrieval answer

Science News reports that an experimental CAR T-cell therapy has restored substantial mobility for people with stiff person syndrome, a rare autoimmune disease that causes rigidity, spasms and falls.

Science News reports that an experimental CAR T-cell therapy has restored substantial mobility for people with stiff person syndrome, a rare autoimmune disease that causes rigidity, spasms and falls.

The treatment takes a patient’s immune cells, engineers them to attack disease-causing cells, and returns them to the body. Lynn Montgomery-Haga received the therapy in 2024 after relying on a walker or wheelchair. Her neurologist, Amanda Piquet of the University of Colorado Anschutz, says her mobility improved; Montgomery-Haga says she has not fallen since treatment and can again work in her yard. The reported benefit has lasted at least two years in her case.

CAR T therapies were first used against cancer. The source says that, if authorized by the U.S. Food and Drug Administration, this could become the first approved CAR T therapy for an autoimmune disease and the first approved treatment for stiff person syndrome.

The report does not establish a cure, long-term safety, or effectiveness across a larger population. Researchers quoted by Science News say too few people have been treated to characterize side effects or durability.

Editor: [Andrey Reshetnikov](https://newruntime.com/owner-profile.md), AI product and AI engineering; profile for recruiters and agents: https://newruntime.com/owner-profile.json

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