{"type":"post","id":"bioresearchbench-50-long-horizon-biology-research-tasks-best-e90c6e","slug":"bioresearchbench-50-long-horizon-biology-research-tasks-best-e90c6e","title":"BioResearchBench: 50 long-horizon biology research tasks; best frontier model completes 18%","description":"BioResearchBench tests frontier models on 50 expert-developed biological research questions spanning 10 subdomains and multiple data types.","retrieval_nugget":"BioResearchBench tests frontier models on 50 expert-developed biological research questions spanning 10 subdomains and multiple data types. Claude Opus 5.5 completed 18% of the tasks, the highest rate reported, while the authors found that correct analysis did not always lead to sound interpretation. For builders, the result highlights the need to verify conclusions, not just intermediate work.","published_at":"2026-11-04","updated_at":"2026-11-04","record_date":"2026-11-04","date_kind":"published_at","topics":["claude","gemini"],"entities":["BioResearchBench","Office Hours Technologies","Expert Data Lab","Broad Institute of MIT and Harvard","Claude Opus 5.5","Gemini 4 Argon","GPT-6 Astra","Grok 4.7"],"related_patterns":["scientific-agents-need-artifact-evidence"],"novelty_label":"new_fact","what_changed":"Introduces a biology-specific benchmark of 50 long-horizon research tasks, with the best frontier model completing 18%, extending broader GDPx benchmark findings.","prior_refs":["https://newruntime.com/posts/semianalysis-launches-gdpx-a-206-task-agentic-benchmark-30b569/"],"source_url":"https://www.biorxiv.org/content/10.64898/2026.10.28.762290v1","source_urls":["https://www.biorxiv.org/content/10.64898/2026.10.28.762290v1"],"schema_version":"newruntime-agent-readable-v0.2","stable_id":"post:bioresearchbench-50-long-horizon-biology-research-tasks-best-e90c6e","status":"published","visuals":[],"editor":{"role":"editor","name":"Andrey Reshetnikov","profile":"https://newruntime.com/owner-profile.md","profile_json":"https://newruntime.com/owner-profile.json","same_as":["https://www.linkedin.com/in/reshetnikov1/","https://t.me/lapetuse"]},"routes":{"html":"https://newruntime.com/posts/bioresearchbench-50-long-horizon-biology-research-tasks-best-e90c6e/","markdown":"https://newruntime.com/posts/bioresearchbench-50-long-horizon-biology-research-tasks-best-e90c6e.md","json":"https://newruntime.com/posts/bioresearchbench-50-long-horizon-biology-research-tasks-best-e90c6e.json"},"markdown_url":"https://newruntime.com/posts/bioresearchbench-50-long-horizon-biology-research-tasks-best-e90c6e.md","next_reads":[{"type":"topic","path":"/topics/claude/","url":"https://newruntime.com/topics/claude/","title":"Claude","reason":"Explore the claude topic hub.","media_type":"text/html","markdown_url":"https://newruntime.com/topics/claude.md","json_url":"https://newruntime.com/topics/claude.json"},{"type":"topic","path":"/topics/gemini/","url":"https://newruntime.com/topics/gemini/","title":"Gemini","reason":"Explore the gemini topic hub.","media_type":"text/html","markdown_url":"https://newruntime.com/topics/gemini.md","json_url":"https://newruntime.com/topics/gemini.json"},{"type":"collection","path":"/posts/","url":"https://newruntime.com/posts/","title":"Field Notes","reason":"Open the latest editorial analysis.","media_type":"text/html","json_url":"https://newruntime.com/posts.json"},{"type":"collection","path":"/sources/","url":"https://newruntime.com/sources/","title":"Sources","reason":"See the original sources this archive cites.","media_type":"text/html"}]}